Medical Informatics


Oregon Health Sciences University
Medical informatics: better technology for better health care

Reproduced with permission from NeXT Computer, Inc.
A Reference Guide to NeXT in Higher Education, Fall 1992
ยช 1992 NeXT Computer, Inc


The 11 faculty members in Biomedical Information Communication Center (BICC) at Oregon Health Sciences University use their cluster of 45 NeXT machines to conduct research in medical informatics, a discipline focusing on the use of information technology in the health-care industry.

Researchers use NeXTSTEP developer tools, including the Application Kit, Interface Builder, and Objective C, according to Kent Spackman, BICC's associate director for research and development. "NeXT has confirmed many times over that it is the fastest development and prototype platform around," he says. "X-Windows and the Macintosh are slow to program and more difficult to operate. I've been using NeXT machines since 1988 and was convinced of its value early on."

BICC has several NeXT-based projects under way. The following are a sampling:

End-user computing. Led by Spackman, researchers are developing physician-station software to enable rapid, high-quality health-care decisions. The software will integrate medical information found in various hospital and clinical databases. Health-care professionals will not only be able to access the database but also to network with colleagues locally and statewide. The NeXT-based workstation will also evaluate laboratory data and monitor the appropriateness of requests for laboratory tests and blood products.

"The workstation will help doctors overcome the problem of information overload in making decisions," says Spackman. "It's a way for doctors to gather information in a form that's very easy to assimilate. Previously, doctors had to consult with other doctors, talk with the nurse and track down a number of other personnel to gather information, which caused a large amount of administrative overhead. All the information available to make a decision was either on paper or on numerous computer systems. The workstation will provide summary information from a variety of sources, which saves time and improves decision making. In the past, treatment decisions were based on a single point in time because doctors did not have time to trace the case history.

"The workstation is to the doctor what Lotus Improv is to the businessperson," he adds. "It's a presentation mechanism and a way to do what-if analyses on medical data."

Image Analysis. Today, most medical decisions depend on visual images. Through their image analysis research, BICC faculty hope to develop methodologies for computer-assisted quantitation of this visual data, which will improve physicians' ability to detect subtle changes in patients' conditions.

Assistant Professor of Dermatology Douglas Perednia is investigating uses of digital images in dermatology. With a National Cancer Institute grant, Perednia is working on various image analysis techniques to improve melanoma screening. Using NeXTdimension, he analyzes and tracks images of patients' skin over time. With this method, Perednia expects small changes-that would not have been detected using traditional methods-will be caught so the melanoma can be removed early.

"With NeXTdimension, we have state-of-the-art, high-end color capabilities," says Spackman. "Plus, the large, high-resolution screen lets us not only view various parts of our research, but a variety of menus and tools as well."

Information retrieval. Assistant Professor of Medicine William Hersh is using the NeXT platform to develop methods for indexing and retrieving information from biomedical literature so answers to clinical and research questions can be more easily and completely acquired. According to Spackman, this work builds on the National Library of Medicine's metathesaurus for translations among different medical terminologies and coding schemes.

"We're using NeXT as a generic UNIX box for this application," says Spackman. "We hope to create a rapid-search indexing option to obtain medical information that's available over the Internet. The application will be similar to Digital Librarian."

Outcomes research. Outcomes research assesses which techniques do or do not work in health care. It provides comparative evaluations of different treatment methods for a given condition. For example; Is a person with a particular ailment best treated as an in-patient or an out-patient? Is it recommended that a patient in a certain condition be transported from a rural location to a hospital or not?

To help doctors make the best decisions when faced with these dilemmas, BICC researchers have devised a series of neural networks that are trained to use data collected from the real world to predict the outcome of medical procedures. These predictive models are then cross-validated on BICC's NeXT network using Zilla, a computationally-intensive application.

"With its massive virtual memory and efficient communication facilities, running Zilla on a network of NeXT machines is like having the capabilities of a supercomputer," says Spackman. "Zilla is a very powerful computational tool."

For more information, please contact:

Kent Spackman, M.D., Ph.D.
Associate Director for Research & Development
Biomedical Information Communication Center
Oregon Health Sciences University
3181 S.W. Sam Jackson Park Road
Portland, OR 97201-3098
(503)494-4502
spackman@ohsu.edu